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What Arcivus Lab brings — and what it needs

What Arcivus Brings

Computational Infrastructure

Dedicated workstation for molecular simulations, AI-assisted literature analysis, construct design, and automation pipelines.

Domain Expertise

Cross-domain fluency in AI, molecular biology, and computational tools — bridging informatics and therapeutic development.

Characterized Target

Fully resolved genetic identity with confirmed pathogenic variant, enabling precise construct design from day one.

Open Platform

Interactive 3D protein visualizer, variant database, and research tools — all open for collaborator use.

What We Need

Wet Lab Access

BSL-2 cell culture facility for transfection/transduction experiments.

AAV Production

Core facility or CRO access for vector packaging.

Expertise

AAV construct optimization, neuronal cell culture, in vivo delivery protocols.

Animal Models

SGCE KO mice for phenotype rescue validation.

Regulatory Guidance

Navigating compassionate use or n-of-1 frameworks in Canada.